Translational Research

Translational Research

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winter (0)
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Nutritional Neurobiology of Autism: Revisiting the Zinc Hypothesis
Genetics Research
May 13, 2026

Nutritional Neurobiology of Autism: Revisiting the Zinc Hypothesis

Andreas Grabrucker, PhD
Recent data support a model in which altered zinc biology may act as a modifiable risk factor within a gene–environment…
Gene Therapy for Mutations in the IQSEC2 Gene
Translational Research
March 18, 2026

Gene Therapy for Mutations in the IQSEC2 Gene

Prof. Andrew Levy, MD, PhD
The IQSEC2 protein is a guanine nucleotide exchange factor for Arf6.  Pathogenic variants in the X-linked IQSEC2 gene are associated…
Animal Models of Autism Spectrum Disorder: Foundations for Translational Therapeutic Research
Translational Research
October 29, 2025

Animal Models of Autism Spectrum Disorder: Foundations for Translational Therapeutic Research

Adrien Eshraghi, MD, MSc, FACS
Adrien Eshraghi, MD, MSc, FACS, a 2022 ARI grant recipient, discusses the ongoing translational research conducted in his lab. He considers…
Vasopressin Biology in Autism: From Biomarker to Treatment Target
Biomedical Research
October 8, 2025

Vasopressin Biology in Autism: From Biomarker to Treatment Target

Karen J. Parker, PhD
Karen J. Parker, PhD, describes scientific barriers to progress in developing laboratory-based diagnostic tests and new medications for patients with…
The autism-associated 16p11.2 microdeletion variant impacts the effects of microbiota disturbances on hippocampal development and behavior throughout the lifespan
Biomedical Research
May 28, 2025

The autism-associated 16p11.2 microdeletion variant impacts the effects of microbiota disturbances on hippocampal development and behavior throughout the lifespan

Manuel DiCicco-Bloom, M.D., a recent 2023 and 2025 ARI Grant Recipient, presents research on the genetic basis of autism, underscoring…
Gestational Influences and Autism – 2023
Biomedical Research Series
April 19, 2023

Gestational Influences and Autism – 2023

Judy Van de Water, PhD
Dr. Judy Van de Water, Ph.D., explores the role of gestational factors in the development of autism. She explains how…
Research Updates on Maternal Autoantibodies and Autism
Causes of Autism
May 19, 2021

Research Updates on Maternal Autoantibodies and Autism

Judy Van de Water, PhD
Judy Van de Water, Ph.D., discusses current machine learning research used to identify several patterns of maternal autoantibodies associated with…
Prenatal stress and neurodevelopment 
Biomedical Research Series
June 6, 2018

Prenatal stress and neurodevelopment 

David Beversdorf, MD
Dr. Beversdorf discusses prenatal stress and its implication in autism etiology. He provides a brief history of autism heredity, epigenetics,…
Gestational Influences and Autism – 2017
Biomedical Research Series
April 12, 2017

Gestational Influences and Autism – 2017

Judy Van de Water, PhD
Dr. Judy Van de Water underscores the importance of innate immunity in adaptive immune responses. She highlights cytokines as master…
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